Permissible subject score below 50%??

Hey folks, Is there any topic/subject such as quant/derivatives where scoring below 50% can be afforded, if yes, how many below 50% subjects can be allowed?

Thanks in advance.

Surely that depends on your results in other sections?..in the 50-70 band ,51 is very different from 68.

I would expect ,<50% in any of the larger weighted sections is more or less game over!